The Amino Acid Sequence of Human Chorionic Gonadotropin

نویسندگان

  • FRANCIS J. MORGAN
  • ROBERT E. CANFIELD
چکیده

Thr Cys Tyr Tyr F?ii Lys Ser. Oligosaccharide side chains are attached at residues 52 and 78. In the preparations studied approximately 10 and 30% of the chains lack the initial 2 and 3 NH,-terminal residues, respectively. This sequence is almost identical with that of human luteinizing hormone (Sairam, M. R., Papkoff, H., and Li, C. H. (1972) Biochem. Biophys. Res. Commun. 48, 530-537). The

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

P-234: Expression of Human Chorionic Gonadotropin (hCG) Hormone Using Chinese Hamster Ovary Cells

Background: Human chorionic gonadotropin (hCG) is a member of glycoprotein hormones family consist of two different non-covalently heterodimeric chains: alpha and beta subunits with 92 and 145 amino acids respectively. This hormone plays an important role in human reproduction and physiology especially for maintenance of the corpus luteum during the first months of pregnancy Materials and Metho...

متن کامل

Identification and Confirmatory Method for Human Chorionic Gonadotropin (hCG) using HPLC/MS/MS Analysis

Author for correspondence: Dr Gam Lay Harn School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Pulau Pinang, Malaysia. Tel: 604-6533888 ext 2208 Fax: 604-6570017 E-mail: [email protected] Abstract As a consequence of the abused of human chorionic gonadotropin αhCG) by male athletes, a reliable detection method for βhCG is highly desired in sport testing. hCG is misused by m...

متن کامل

Isolation and amino acid sequence of the alpha-subunit of follicle-stimulating hormone from equine pituitary glands.

Six hundred milligrams of follicle-stimulating hormone (FSH), containing 110 NIH-FSH-S1 units/mg, was isolated from 9 kg of equine pituitary glands. The equine FSH was dissociated into alpha- and beta-subunits. A tentative amino acid sequence of the alpha-subunit was determined. The alpha-subunit contained 82 amino acids. The equine FSH-alpha is shorter by 10 to 14 amino acids at the NH2 termin...

متن کامل

O-32: Effects of Intrauterine Injection of Recombinant Human Chorionic Gonadotropin before Embryo Transfer on Outcome of In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Randomized Clinical Trial

Background: To evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhCG) before embryo transfer (ET). Materials and Methods: In this randomized placebocontrolled clinical trial, a total number of 182 infertile patients undergoing their first in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) were randomly assigned to receive 250 μg i...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002